What does CML stand for?

The Philadelphia chromosome as seen by fluorescent in situ hybridization (FISH). Chronic myelogenous leukemia ( CML ), also known as chronic myeloid leukemia, is a cancer of the white blood cells.

What is the difference between chronic myelogenous leukemia and CML?

Chronic myelogenous leukemia. It is a form of leukemia characterized by the increased and unregulated growth of myeloid cells in the bone marrow and the accumulation of these cells in the blood. CML is a clonal bone marrow stem cell disorder in which a proliferation of mature granulocytes ( neutrophils, eosinophils and basophils)...

Can a stem cell transplant cure CML?

Stem cells are cells that go on to form other types of cell. In this case, stem cells from your bone marrow are transplanted, which can produce healthy white blood cells. A stem cell transplant can potentially cure CML, although its a very intensive treatment and is not suitable in most cases.

What are the treatment options for CML?

Treatment for CML is usually started straight away to help slow down its progression and keep it under control. The main treatments for CML are medicines called tyrosine kinase inhibitors that stop the cancer cells growing and multiplying. They can help keep CML under control if taken for life. These medicines include:

What is chronic myelogenous leukemia (CML)?

Overview Chronic myelogenous leukemia (CML) is an uncommon type of cancer of the bone marrow — the spongy tissue inside bones where blood cells are made. CML causes an increased number of white blood cells in the blood.

What is a CML certificate?

A CML Certificate is granted where the consultant has supervised the building of the property and confirms that it has been built in accordance with the plans and to a satisfactory standard. CML Certificates tend only to cover the property for a shorter term of around 6 years and there must be proven negligence...

What is capital market line (CML)?

Key Takeaways 1 The capital market line (CML) represents portfolios that optimally combine risk and return. 2 CML is a special case of the CAL where the risk portfolio is the market portfolio. ... 3 The intercept point of CML and efficient frontier would result in the most efficient portfolio called the tangency portfolio. More items...

What is the difference between the CML and SML?

The SML is derived from the CML. While the CML shows the rates of return for a specific portfolio, the SML represents the market’s risk and return at a given time, and shows the expected returns of individual assets.

Is a stem cell transplant the best treatment for CMML?

This type of transplant is not a standard treatment for patients with CMML because their bone marrow has abnormal stem cells. For an allogeneic stem cell transplant, the patient gets blood-forming stem cells from another person -- the donor.

What is a bone marrow transplant for CML?

Bone marrow transplant. For CML, you usually have a bone marrow transplant using bone marrow from a donor. This is called an allogeneic transplant. The bone marrow is collected from your donor before your chemotherapy. After your treatment you have the bone marrow cells through a drip into a vein.

What is the treatment for chronic myelomonocytic leukemia (CMML)?

Stem cell transplant (SCT) is the only treatment that can cure chronic myelomonocytic leukemia (CMML). In this treatment, the patient gets high-dose chemotherapy often along with radiation to the entire body to kill the cells in the bone marrow (including the abnormal bone marrow cells).

Is stem cell transplant a common treatment for chronic meyloid leukemia?

Stem cell transplant is not a common treatment for chronic meyloid leukemia (CML) today. In the past, before tyrosine kinase inhibitors (TKIs) were available, SCT was often used to treat CML. Now, TKIs are the standard treatment, and transplants are being used far less often.

How is CML treated? Targeted therapy drugs are the main treatment for chronic myeloid leukemia (CML), but some patients might also need other treatments.

What are the treatment options for accelerated phase CML?

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